Zucker (fa/fa) Rat

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منابع مشابه

Ontogeny of hyperphagia in the Zucker ( fa/ fa) rat.

The ontogeny of hyperphagic behavior in the Zucker fatty ( fa/ fa) rat was examined. Wild-type, +/ fa, and fa/ fapups aged postnatal day 5( P5), P9, P12, P15, and P18 were evaluated using a test that measured ingestive behavior independent of the dam. The independent ingestive test consisted of giving pups access to a test solution [half-and-half (cream and milk)] on a tissue on the floor of a ...

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Regulation of food intake during growth in the Zucker rat.

I. Food intake and rates of protein, lipid and energy deposition during growth were measured for lean and congenitally obese (fatty) Zucker rats offered from 34 d of age to slaughter at 66 d of age, one of six semi-synthetic diets containing casein (C) in the following amounts (g Clkg): 40C, moC, 150C, 3wC, 500C and 700C. 2. In Expt I, groups of four male rats were offered each diet to appetite...

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Microvascular retinopathy in the Zucker diabetic fatty rat.

PURPOSE To determine if quantifiable morphometric signs of retinopathy occur in the Zucker diabetic fatty rat (ZDF/Gmi-fa, formerly designated ZDF/Drt), a partially inbred strain in which the genetic propensity for diabetes is only expressed in obese males. METHODS Retired diabetic (ZDF/Gmi-fa) and control lean Zucker (fa/+) breeder rats were examined for quantifiable evidence of microvascula...

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Cellularity of adipose depots in the genetically obese Zucker rat.

Cell size and number of three adipose depots, epididymal, retroperitoneal, and subcutaneous, were determined during growth of the obese Zucker rat ("fatty") and nonobese Zucker control. Cellularity of these depots in the adult "fatty" was compared with that in nonobese controls and in nonobese Zucker rats made obese by ventromedial hypothalamic lesions. Epididymal and retroperitoneal depots in ...

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Respiratory muscle weakness in the Zucker diabetic fatty rat.

The obesity epidemic is considered one of the most serious public health problems of the modern world. Physical therapy is the most accessible form of treatment; however, compliance is a major obstacle due to exercise intolerance and dyspnea. Respiratory muscle atrophy is a cause of dyspnea, yet little is known of obesity-induced respiratory muscle dysfunction. Our objective was to investigate ...

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ژورنال

عنوان ژورنال: ILAR Journal

سال: 1990

ISSN: 1084-2020

DOI: 10.1093/ilar.32.3.4